One hundred years ago today — May 30, 1913 — Red Sox outfielder Harry Hooper became the first player to lead off both games of a doubleheader with a home run.
Hooper did it in Washington against pitchers Bob Groom and Walter Johnson.
Chris Jaffe has more details at The Hardball Times. It would be more than 80 years before it happened again. On July 5, 1993, Rickey Henderson of the A's connected twice. Baltimore's Brady Anderson did it on August 21, 1999.
Boston split the twinbill with the Senators, losing the opener 4-3 and beating Johnson in the second game 1-0.