On April 20, 1912, the New York Yankees* played the Boston Red Sox at Fenway Park at 3 PM.
On April 20, 2012, the New York Yankees will play the Boston Red Sox at Fenway Park at 3 PM.
* - The team was actually known as the Highlanders at that time.
According to the Red Sox's Fenway Park 100 website, both teams will wear throwback 1912 uniforms for the rivals' first meeting of the season. Boston won that 1912 game, the first major league game played in the new park, 7-6 in 11 innings.